Description
Zoom webinar:
https://fz-juelich-de.zoom.us/j/67716299814?pwd=Q3dBRXZQa3NLL1Y2TVYvUlBqV0lQQT09
Kenncode: 749254
Chair: Kathleen S. Rockland, Jordan DeKraker
Introduction
Imaging of 2D post-mortem tissue sections presents challenges due to potential differences in digitized pixel intensities across batches of acquired tissue. This issue is particularly pronounced in human in vitro autoradiography, where chemical fixation is not possible and the brain's size prohibits uniform shock freezing. Instead, the donor brain must be sectioned into...
Introduction
Structural MRI-derived population average cortical surfaces such as FreeSurfer's (FS) fsaverage 'fsavg' (Fischl 2012) and Human Connectome Project's (HCP) fs_LR (Van Essen et al., 2012) serve as reference frameworks for multimodal data integration.
The cortical surface extracted from the high-resolution 3D-reconstructed histological BigBrain model (Amunts et al., 2013,...
The ability to process and analyze large and complex neuroimaging datasets is crucial to develop computer simulations of the brain. A focus of significant interest is to model the hippocampus, a brain structure integral to memory formation and emotional regulation. This study introduces a state-of-the-art algorithmic pipeline for big data scaling and enhanced surface reconstruction of the...
One of the major challenges to carrying out in vivo neuroanatomical analyses is that there is significant regional cytoarchitectural variation that is often difficult to capture by MRI. As a result, parcellation of brain regions is often limited to a scale too coarse for the understanding of their functions. While this is a challenge for many regions of the brain, the insula is one such region...
One of the biggest challenges in understanding the brain is being able to discern how the molecular, cellular and systemic levels of organization relate to each other to enable cognitive functions and the control of behavior. The combined analysis of the cytoarchitectonic segregation of the cerebral cortex and of the regional and laminar distribution patterns of multiple neurotransmitter...
