Abstract:
Much research has suggested that the organization of functional brain networks may help us understand risk for the development of psychopathology. However, relatively little of this work has focused on current advances in modeling the structure of psychopathology, such as the recent work by the Hierarchical Taxonomy of Psychopathology Initiative (HITOP). Here we present data on the degree to which disruptions in the organization of functional brain connectivity can predict variability in psychopathology at different levels of the HITOP Taxonomy, with the strongest evidence for prediction at the level of the “p-factor” or general psychopathology.
