17–18 Jun 2025
Virtual
Europe/Berlin timezone

ATP Restriction Influences Outcomes in Brain-in-a-Dish Models Utilizing EDLIF and ED-STDP

P-2
18 Jun 2025, 14:47
2m
Zoom

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Poster & advertisement flash talk Poster teasers

Speaker

Matias Urrea

Description

Biological neurons are remarkably energy-efficient, capable of performing complex computations with minimal energy consumption. Understanding these mechanisms can inform the design of efficient computational models and energy-aware learning systems. In this study, we implemented energy-dependent neuron and synaptic plasticity models—EDLIF (Energy-Dependent Leaky Integrate-and-Fire) and EDSTDP (Energy-Dependent Spike-Timing-Dependent Plasticity)—using NEST. We developed a simulated environment/arena in NEST where a network of biophysically plausible artificial neurons control a two-wheeled robot that learns to avoid obstacles based on proximity sensor data. Our network, driven by synaptic plasticity, learned to steer away from obstacles based on sensory input. We further observed that modifying ATP-related parameters significantly affected performance, suggesting that the task's success is closely tied to energy availability and usage. These results emphasize the role of metabolic constraints in learning and offer insights for the development of energy-efficient neuromorphic systems.

Acknowledgements

Powered@NLHPC: This research was partially supported by the supercomputing infrastructure of the NLHPC (CCSS210001)

References

https://doi.org/10.1111/ejn.15326
https://doi.org/10.1101/2023.10.25.563409

Preferred form of presentation Poster & advertising flash talk
Topic area Models and applications
Keywords EDLIF, ATP, Brain-in-a-dish
Speaker time zone UTC-4
I agree to the copyright and license terms Yes
I agree to the declaration of honor Yes

Primary author

Matias Urrea

Co-authors

Mr Camilo Jara (CENIA) Dr Christ Devia (CENIA) Dr Mircea Petrache (CENIA) Dr Pedro Maldonado (CENIA) Samuel Madariaga (Universidad de Chile)

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