Speaker
Sylvio Haas
(DESY)
Description
Within this contribution, the technique of Small- and Wide-Angle X-ray Scattering (SAXS/WAXS) will be introduced in the context of nanostructure characterization in 3D. The focus is on the 3D orientation analysis of fiber-based structures using SAXS tensor tomography.
Three selected examples will be shown:
- Orientation analysis of collagen in breast cancer tissues. An understanding of the 3D architecture of the tumor environment is important to guide the development of novel therapeutic approaches. Especially the collagen orientation, diameter, and metal accumulation are of interest.
- Myelin quantification and orientation in multiple sclerosis (MS) human brain sections. Since MS is a demyelinating disease, quantifying the changes in myelin levels, integrity, and neuronal tracts enables an unprecedented understanding of the disease progression.
- What can be done with SAXS/WAXS imaging in the research field of archaeology? An example of a heritage object investigation will be shown.
Primary author
Sylvio Haas
(DESY)
Co-author
Andre Luiz Coelho Conceicao
(DESY)
