The cerebral cortex is made up of roughly six horizontally organized layers with unique cytoarchitectural properties distributed across the cortical mantle. This gradual variation of laminar structure is a fundamental principle of cortical organization. The similarity of regions in their laminar structure, with roots in development, is suggested to relate to the likelihood, strength and...
Introduction One important feature of the human brain is structural asymmetry in the homologous contralateral anatomical regions. Left-right asymmetries of cortical thickness and surface area exist widely across the cortical mantle but intracortical microstructure asymmetry is rarely studied. Here we evaluate the asymmetry of microstructural organization in the human cortex combining *post...
Background. The claustrum is a “sheet-like” telencephalic grey matter structure, wrapped by the capsulae extrema and externa, and tucked between the putamen and insula. Anatomical studies have revealed that the claustrum is one of the most connected of any brain structure (by volume), and demonstrates reciprocal connections across the entire cortical mantle. Though this remarkable...
The hippocampus (or archicortex) has a complex folded laminar structure that can be fully appreciated in the multiplanar views afforded by 3D BigBrain [1]. Here, we will look at how analysis of the hippocampus and hippocampal subfields can be performed using the same principles as surface-based analysis of the neocortex and neocortical parcels [2]. That is, at high resolution the various folds...