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IP Retreat Healthy Planet

7 May 2025
Leipziger KUBUS
Europe/Berlin timezone

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Contribution List

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7. Introduction to the IP
Stefan Scholz
07/05/2025, 09:00
8. Sarah Stevens (ZELLTOX): Endocrine and metabolism disrupting chemicals in plastic food packaging: Addressing the unknowns
07/05/2025, 09:15

Authors: Sarah Stevens, Molly McPartland, Zdenka Bartosova, Johannes Völker, Martin Wagner

Abstract:
Plastics are chemically highly complex materials with more than 16 000 chemicals likely used or present in plastics. Of these, more than one quarter is known to be hazardous, while more than 10 000 lack basic data on identity, functionality, and toxicity. In addition, plastics contain...
9. Maolida Nihemaiti (EAC): Novel highly polar sulfonated disinfection by-products in drinking water: identification and formation mechanisms
07/05/2025, 09:30

Authors: Maolida Nihemaiti, Bettina Seiwert, Maik Icker, Jon Wullenweber, Mathias Ernst, Andreu Fargas-Marquès, Laura Kahle, Oliver Lechtenfeld, Thorsten Reemtsma

Abstract:
"Disinfection is a critical step during drinking water production and distribution to prevent waterborne disease. However, the chemical disinfectants (e.g., chlorine) can react with water matrices (organic matter,...
10. Milena Latz (EAC): High-resolution TD-PTR-MS as a novel analytical technique for nanoplastic detection and quantification in environmental samples
07/05/2025, 09:45

Authors: Milena Latz, Dušan Materić

Abstract: "Research during recent years has showed that plastic pollution has already penetrated all areas of the world. Not only in urban-, but also in rural regions, environmental research showed high contamination of primary and secondary plastic debris. While the majority of research focuses on plastic particles >1 µm (macro- and microplastics),...
12. Alain Hoyek (EXPO): Identifying Source-Specific Contaminant Fingerprints in Wastewater and Surface Waters, and Key Features for Bioactivity and Toxicity Prediction Using Machine Learning
07/05/2025, 11:15
13. Marina Pozhidaeva (COMPBC): MeSyTo - Advancing Data Interoperability in Toxicology and Pharmacology Through Standardized Metadata and Ontologies Data Science and Modelling
07/05/2025, 11:30

Author: Marina Pozhidaeva

Abstract: "Tackling chemical pollution as part of the Triple Planetary Crisis requires data science-based solutions that enable comprehensive environmental monitoring, risk assessment, and policy development. However, the lack of standardized and interoperable metadata in toxicology and pharmacology hinders the effective integration and reuse of critical data. The...
14. Ilhan Mutlu (COMPBC): From Incomplete to Insightful: Curating Spatially Annotated Monitoring Data with CleanGeoStreamR
07/05/2025, 11:45

Authors: Ilhan Mutlu, Jana Schor, Jörg Hackermüller

Abstract: "Environmental monitoring data is frequently compromised by inconsistent, incomplete, or erroneous spatial metadata, which restricts its effective utilization in research and informed decision-making processes. Recently, we have developed the CleanGeoStreamR to overcome such challenges in an automated way. CleanGeoStreamR...
15. Dilshana Shanavas Rasheeda (COMPBC): Can We Use AI to Provide Quantitative Predictions for Chemical Bioactivity and Toxicity?
07/05/2025, 12:00

Authors: Dr. Dilshana Shanavas Rasheeda, Prof. Dr. Jana Schor

Abstract: "Understanding and predicting chemical bioactivity is central to drug development, chemical safety, and environmental risk assessment. However, large numbers of unlabelled compounds remain unexplored due to the cost and scale of experimental testing. In this work, we investigate the potential of artificial intelligence...
16. Samuel Türken (ETOX): Additive Effects of PFAS Mixtures on Acute Toxicity and Phenotypic Endpoints in Zebrafish Embryos
07/05/2025, 14:00

Authors: Samuel Türken, Jasmin Stockhause, Renee Owen, Lena Knödler, Janet Krüger, Nils Klüver, Dorte Herzke, Line Småstuen Haug, Oddvar Myhre, Paul Michaelis, Tamara Tal, Wibke Busch

Abstract: "Additive Effects of PFAS Mixtures on Acute Toxicity and Phenotypic Endpoints in Zebrafish Embryos
Samuel Türken1, Jasmin Stockhause1, Renee Owen1, Lena Knödler1, Janet Krüger1, Nils Klüver1, Dorte...
17. Cassandra Uthoff (MOLTOX): Impact of Acute Pesticide Exposure on Honeybee Worker (Apis mellifera) Behaviour and Gut-Brain Molecular Changes
07/05/2025, 14:15

Authors: Cassandra Uthoff, Abdulrahim T. Alkassab, Beatrice Engelmann, Ulrike-Rolle Kampczyk, Sven-Bastiaan Haange, Jens Pistorius, Andreas S. Thum, Nico Jehmlich, Martin von Bergen

Abstract: Honeybee colonies, as superorganisms, depend on effective communication and coordination that can be disrupted by pesticides on multiple levels. To understand this, we studied the molecular changes in...
18. Ayesha Siddique (ETOX): Integrating NAMs and Field Studies for ERA
07/05/2025, 14:30

Authors: Ayesha Siddique, Naeem Shahid, Matthias Liess and many others

Abstract: "Assessing pesticide effects across different biological levels remains a significant challenge, as field and laboratory studies are often conducted independently, leading to fragmented insights. Field studies, like those by Liess et al. (2021), have shown that pesticides can cause adverse effects even at lower...
19. Paula Reichelt (IMMU): Impact of the Covid-19 pandemic lockdown and associated changes of exposure to bioactive chemicals and immune parameters in children
07/05/2025, 15:15

Authors: Paula Reichelt, Georg Braun, Arkadiusz Pierzchalski, Naroa Lopez-Herguedas, Sebastian Thieme, Beate Escher, Ana Zenclussen

Abstract: "Background
Children's immune systems significantly differ from adults. Particularly their adaptive immune defense is still developing. Contact with pathogens plays a crucial role, as with each infection, the immune system learns to specifically...
20. Cornelius Goerdeler (MOLTOX): 13C Metabolic Tracing in Human Adipocytes for Assessing Metabolism-Disrupting Properties
07/05/2025, 15:30

Authors: Beatrice Engelmann, Helen Broghammer, Alix Sarah Aldehoff, Martin Wabitsch, Kristin Schubert, Matthias Blüher, John T. Heiker, Ulrike Rolle-Kampczyk, Martin von Bergen

Abstract: Exposure to certain environmental chemicals, including phthalates, may promote the development of metabolic diseases, including obesity. Since specific regulatory methods to identify metabolism-disrupting...
21. Katharine Heyl (UPR): EU plastic governance for healthy soils
07/05/2025, 15:45

Authors: Jessica Stubenrauch & Katharine Heyl

Abstract: "Soils are key in overcoming the interlinked climate and biodiversity crises. Having or restoring healthy soils is thus essential to achieve the goals of the Paris Agreement and the Convention on Biological Diversity. However, globally, soil degradation is rising including by plastic pollution. Plastic pollution is caused by large...
22. Alix Sarah Aldehoff (MOLTOX) Advanced proteomics approaches hold potential for risk assessment of metabolism disrupting chemicals as omics-based NAM
07/05/2025, 16:00

Authors: Alix Sarah Aldehoff, Isabel Karkossa, Helen Broghammer, Sontje Krupka, Juliane Weiner, Cornelius Goerdeler, Rima Nuwayhid, Stefan Langer, Martin Wabitsch, Ulrike Rolle-Kampczyk, Nora Klöting, Matthias Blüher, John T. Heiker, Martin von Bergen and Kristin Schubert

Abstract: The concept of metabolic disruption through exposure to chemicals has expanded our understanding of how...
23. All Poster Abstracts
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