Using the multilevel human brain atlas in reproducible workflows with siibra-python

Timo Dickscheid

Institute of Neuroscience and Medicine, Structural and functional organisation of the brain (INM-1), Research Centre Jülich, Germany
Institute of Computer Science, Heinrich-Heine-University Düsseldorf, Germany
Helmholtz AI, Research Centre Jülich, Germany

Thursday, 20 June 2024, 14:00 CEST | 17:00 IST | 8:00 EDT

siibra is a software tool suite that allows to access the multilevel human brain atlas by providing access to reference templates at different spatial scales, complementary brain parcellations maps, and multimodal regional data from different sources which is linked to brain anatomy at different spatial scales. Besides interactive exploration in the 3D web viewer siibra-explorer, the framework can be leveraged for scripting, reproducible workflows and application development using the siibra-python programming library.
This session will introduce the core concepts of siibra-python and demonstrate a range of typical programming patterns to use the atlas. It will cover practical coding exercises demonstrating how to fetch brain region maps, access high-resolution microscopy data including the BigBrain dataset, and extract multimodal regional features such as cortical thicknesses, cell and neurotransmitter densities, gene expressions, and connectivity data. Participants will gain first insight of the features of siibra-python to enhance their ability to perform advanced neuroimaging analyses with data coming from different modalities and resolutions. 

Requirements

For preparation, participants should register for an EBRAINS account (https://ebrains.eu/register) and  bring a notebook with an up-to-date web browser (recent versions of Chrome or Firefox are recommended) for the hands-on examples. The examples will be run on pre-built Jupyter notebooks, which will be provided for downloading.