Description
co-Chairs: Jordan DeKraker, Timo Dickscheid
Introduction: Quantitative maps of neurotransmitter receptor densities are important for characterizing the brain's molecular organization. We previously presented a 3D reconstruction pipeline for 2D autoradiographs to create 3D atlases at up to 50μm resolution [1]. Here, we use 3D reconstruction of autoradiographs from a macaque hemisphere to investigate patterns of receptor distribution...
Optical approaches for in vivo neural monitoring offer a precious window on brain functions and on the mechanisms of development, ageing or disease progression. Nonetheless, the existing methods still struggle to capture in situ the complex biomolecular alterations that accompany physiological and pathological dynamics. As a result, our grasp on the multifaceted components of brain...
Introduction:
In 2013, we published BigBrain1 (BB1), a high-resolution (20µm^3) histological 3D-reconstructed model of the human brain (Amunts et al., 2013). Over the past several years, progress has also been made on BigBrain2 (BB2) (Mohlberg et al., 2022; Lepage et al., 2023), with preliminary reconstruction and segmented volumes [white matter (WM) and gray matter (GM)] now...
Introduction
Brain atlases derived from MRI are a common tool for neuroscientists to understand the anatomy of the brain. However, as MRI has a limited resolution, these tools give a poor insight into fine structures [1]. This is why different groups have developed microscopy-based atlases which nevertheless require hours of sequential cutting and mapping [2,3]. Thus, we unveil a...
