9–11 Sept 2024
Palazzo della Salute
Europe/Rome timezone
!!! Registration open for remote participation only !!!

The BigMac Dataset: combining multi-contrast MRI and microscopy in the macaque brain

9 Sept 2024, 14:45
1h 30m
Elettra (Palazzo della Salute)

Elettra

Palazzo della Salute

Hands-on session Hands-on Session 3

Speakers

Amy Howard (Wellcome Centre for Integrative Neuroimaging (FMRIB Centre), University of Oxford) Silei Zhu (Wellcome Centre for Integrative Neuroimaging (FMRIB Centre), University of Oxford)

Description

The BigMac dataset is an open access resource combining in vivo MRI, extensive postmortem MRI and multi-contrast microscopy for multimodal characterisation of a single whole macaque brain. The data is highly complementary to BigBrain facilitating complementary analyses across scales, datasets and species. Crucially, the BigMac MRI and microscopy data have been carefully co-registered together to facilitate quantitative multimodal analyses and data-fusion approaches which more heavily rely on multiple modalities being acquired in the same subject. This session will start with an introductory talk where I will outline the acquisition and curation of the BigMac data, alongside some example applications from the lab. The latter part of the session will feature hands-on interactive notebooks where participants can explore the BigMac data and curated outputs, as well as running microscopy-informed “hybrid” tractography and performing MRI-microscopy comparisons.

Presentation materials

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